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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SET
All Species:
31.21
Human Site:
S175
Identified Species:
52.82
UniProt:
Q01105
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01105
NP_001116293.1
290
33489
S175
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Chimpanzee
Pan troglodytes
XP_001159448
829
93320
S175
S
T
E
I
K
W
K
S
G
K
E
R
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001110579
290
33486
S175
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Dog
Lupus familis
XP_851207
289
33547
S174
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQU5
289
33359
S174
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Rat
Rattus norvegicus
Q63945
289
33387
S174
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518746
289
33461
S174
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Chicken
Gallus gallus
NP_001025862
277
32133
S162
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Frog
Xenopus laevis
NP_001084174
278
32182
A162
S
T
E
I
K
W
K
A
G
K
D
L
T
K
R
Zebra Danio
Brachydanio rerio
NP_958876
275
31780
A162
S
T
E
I
K
W
K
A
G
K
D
L
T
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53997
269
30976
T163
D
W
P
A
S
T
S
T
P
I
K
W
K
E
G
Honey Bee
Apis mellifera
XP_001120556
314
35895
E163
S
T
P
I
R
W
K
E
G
A
D
L
T
K
R
Nematode Worm
Caenorhab. elegans
Q18240
312
35855
N161
T
E
I
E
W
K
E
N
K
K
P
P
F
P
E
Sea Urchin
Strong. purpuratus
XP_001175529
322
36489
P167
A
T
P
I
R
W
K
P
N
K
D
L
T
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.5
99.6
96.2
N.A.
94.1
94.1
N.A.
86.5
88.6
86.2
83.7
N.A.
57.9
52.2
33.9
55.5
Protein Similarity:
100
33.2
99.6
96.2
N.A.
95.8
95.8
N.A.
87.9
90
90
89.6
N.A.
74.1
70.6
53.8
70.1
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
0
73.3
6.6
60
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
80
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
15
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
79
0
0
0
0
% D
% Glu:
0
8
72
8
0
0
8
8
0
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
79
0
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
86
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
72
8
86
0
8
86
8
0
15
79
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
79
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
22
0
0
0
0
8
8
0
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
15
0
0
0
0
0
0
8
0
0
72
% R
% Ser:
79
0
0
0
8
0
8
58
0
0
0
0
0
0
0
% S
% Thr:
8
86
0
0
0
8
0
8
0
0
0
0
79
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
8
86
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _